This book constitutes the refereed proceedings of the First International Conference on Grid and Pervasive Computing, GPC 2006, held in Taichung, Taiwan, in May 2006. The 64 revised full papers were carefully reviewed and selected from 267 submissions. The papers are organized in topical sections on grid scheduling, peer-to-peer computing, Web/grid services, high performance computing, ad hoc networks, wireless sensor networks, grid applications, data grid, pervasive applications, semantic Web, semantic grid, grid load balancing, wireless ad hoc/sensor networks, and mobile computing.