This text is a fully integrated summary of all aspects of clinical neurophysiology. It is written by nationally recognized experts who work together at Mayo Clinic. All the authors are heavily involved in the teaching of clinical neurophysiology to residents in neurology, neurosurgery and physical medicine, and to poet-residency fellows in EEG, EMG, autonomic disorder, sleep disorders, peripheral nerve diseases, and muscle diseases. The first section is a review of the basics of clinical neurophysiology. The second considers the assessment of disease by anatomical system. The third explains how clinical neurophysiologic techniques are used in the clinical assessment of diseases of the nervous system. This thoroughly revised Second Edition includes new approaches and a new chapter on the clinical neurophysiology of pain. The clinical problems in which each of the clinical neurophysiologic approaches can add to the diagnosis and management of neurologic disease are detailed, especially the assessment of clinical symptom complexes with electroencephalography (EEG). The discussions of pediatric EEG disorders, ambulatory EEG, new equipment and digital analyses, magneto-EEG, electromyographic (EMG) techniques, motor unit number estimates, myoclonus on surface EMG, segmental sympathetic reflex, and postural normotension have been expanded. Chapters on EMG quantified and single fiber EMG have been reorganized, and major revisions have been made in the discussion of sensory potentials, somatosensory evoked potentials, acoustic reflex testing, cardiovagal function, physiologic testing of sleep, and assessment of sleep disorders. New approaches are discussed in each of the four chapters on monitoring neural function during surgery, particularly with motor evoked potentials.