The two volume set LNCS 4131 and LNCS 4132 constitutes the refereed proceedings of the 16th International Conference on Artificial Neural Networks, ICANN 2006, held in Athens, Greece, in September 2006.

The 208 revised full papers presented were carefully reviewed and selected from 475 submissions. The 103 papers of the first volume are organized in topical sections on feature selection and dimension reduction for regression, learning algorithms, advances in neural network learning methods, ensemble learning, learning random neural networks and stochastic agents, hybrid architectures, self organization, connectionist cognitive science, cognitive machines, neural dynamics and complex systems, computational neuroscience, neural control, reinforcement learning and robotics applications, robotics, control, planning, as well as bio-inspired neural network on-chip implementation and applications. The second volume contains 105 contributions related to neural networks, semantic web technologies and multimedia analysis, bridging the semantic gap in multimedia machine learning approaches, signal and time series processing, data analysis, pattern recognition, visual attention algorithms and architectures for perceptional understanding and video coding, vision and image processing, computational finance and economics, neural computing in energy engineering, applications to biomedicine and bioinformatics, applications to security and market analysis, as well as real world applications.