This book constitutes the refereed proceedings of the 10th International Conference on Foundations of Software Science and Computation Structures, FOSSACS 2007, held in Braga, Portugal in March/April 2007 as part of ETAPS 2007, the European Joint Conferences on Theory and Practice of Software.

The 25 revised full papers presented together with the abstract of 1 invited talk were carefully reviewed and selected from 103 submissions. The papers cover a broad spectrum on theories and methods to support analysis, synthesis, transformation and verification of programs and software systems. In particular the following topics are dealt with: algebraic models, automata and language theory, behavioral equivalences, categorical models, computation processes over discrete and continuous data, infinite state systems computation structures, logics of programs, modal, spatial, and temporal logics, models of concurrent, reactive, distributed, and mobile systems, process algebras and calculi, semantics of programming languages, software specification and refinement, type systems and type theory, fundamentals of security, semi-structured data, program correctness and verification.