Belonging to the prestigious "Rochester Conference Series", ICHEP 2006 is the most important international conference in 2006 on high energy physics. These proceedings provide a comprehensive review of recent developments in experimental and theoretical physics of particles at high energies. This volume features articles on the latest results in all the essential areas: particle astrophysics and cosmology, neutrino physics, lattice calculations and computational quantum field theory, heavy ion collisions and quark matter, hard and soft interactions in quantum chromodynamics, electroweak physics, extra dimensions and extra gauge bosons, CP violation and rare decays, top and Higgs search, hadron spectroscopy and exotics, heavy quark physics, GRID distributed analysis, R&D for future accelerators, detectors and new facilities, and mathematical aspects of quantum field theory and string theory.